Experience Psychedelic Transformation

H2: The world’s first Legal Psilocybin Retreat Centre PIONEERS ETC


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The world is experiencing a crisis.

It’s hard for a lot of people to imagine their life being better. 

The challenge with profound transformation is it often requires a leap of faith, to step into the unknown, hoping for the changes we want, but not really knowing what we’ll have to go through to get there. 

What we’re hoping to experience is so radically different from where we are now, and we’ve known this reality for so long that we start to believe it has to be this way forever. This is what most people living with levels of anxiety, stress or depression often report. 

They know their life isn’t  and have even reported thinking there is something wrong with them, or their brain. These feelings can be crippling and you can start to feel trapped. Especially when you have to hold down an identity that you’ve created for the outside world to see. 

But something has got you here. You’re ready for a change.

Perhaps you feel you’ve tried everything else. 

Maybe you saw some small changes take place, or things got better for a while. 

You may have been working through some issues for a while, tried all the things, and while you might experience short term success, time passes and you find yourself back where you didn’t want to be. 

Unable to shake that nagging feeling that things don’t need to be this way and that you can somehow break free from this cycle and create a brighter, more peaceful life for yourself. It might feel like you need to rewire your brain.

If you’re reading this, chances are, the reports of the long-lasting benefits of psychedelics have peaked your curiosity. 

And for good reason, the results/impact is hard to ignore. 

Research is showing that taking psychedelics can significantly change personality traits that usually stay stagnant in adults. Changes that people had never thought possible.

With reports of depression entering an epidemic and high levels of stress and anxiety being reported in a scarily high number of professionals. It’s clear that something is wrong and the solutions we have in place aren’t working

Cover up, normalise high levels of stress and numb the symptoms with antidepressants, other drugs and alcohol, and with the ‘war on drugs’ and the associated ‘hippie’ behaviour, psychedelics and their profound healing effects have stayed buried past. 

Until now.

We believe that you deserve access to safe, legal and transformative psychedelics experiences. We believe in the power of the empowered individual. You each have your missions and we’re tired of seeing you stuck in your own heads, getting in your own way of realising your goals of a better life for yourself and those around you. 

We saw the need to create a space where professionals can come to work on their shit, in a safe, private space, away from their everyday lives. Where they can connect with other individuals, also committed to bettering their lives. 

We made it our mission to create a program with roots firmly planted in 

As stewards of the industry, we have partnered with XXXXX to ensure our programs are 

You now have the opportunity to join over 500 guests who have embarked on a journey towards themselves, to ditch the shackles and free themselves, creating an opportunity to pave the way for a better future.

More Than Just A Trip

Our retreats are centred around the ceremonial use of high-dose, legal psilocybin truffles, but our retreat results, go beyond that. 

We have curated an expert team of therapists, breathwork instructions etcs

And designed an experience that blends the best of ancient wisdom, with cutting edge science, to deliver what our clients are reporting as, “one of the most impactful experiences of their lives’.

Here are some of the incredible results that our studies have shown.





Our participants go from below the national average of wellbeing to above the average. A significant 10% increase.


Depressive symptoms remained lowered by 42.4%.* [Such as insomnia, rumination, sad mood, low energy, difficulty with concentration, and fluctuations in appetite.]


The degree of connection that each participant experienced to themselves, others, and the wider world, more than doubled after Synthesis, an increase of 118%.


The degree of fear and stress reported by participants decreased by and remained lowered by 13.8%.

*Data was collected and analysed independently in participation with Imperial College London. Baseline was two weeks before a Synthesis retreat and during. Follow up was two and four weeks after. Data and analysis can be found here.

quitting smoking, and overcoming alcohol addiction. As well as the groundbreaking study on psilocybin in the treatment of depression, researchers have shown that psilocybin could also be used to treat anxiety suffered by people with terminal illness. 


First off, we administer the truffles in a way to reduce physical discomfort and nausea. Then, taking into consideration your intention, sensitivity, and previous experience, we optimize the best dosage for you. Finally, we integrate the latest findings and best practices from the psychedelic research community to ensure your experience is as profound and effective as possible.

In committing to this experience, you will be a pioneer in your own right, joining a specially curated list of attendees who are contributing to the next conscious evolution of humanity in a significant way.

Here’s what the mushrooms could show you:















*While each experience is unique, these are the most commonly reported benefits.





At Synthesis, we’re not here to ‘fix you’. We’re simply here to be your guide, to hold space for you in safe and supported setting where. As pioneers we have just created this amazing space with the research etc. 



Based in the Netherlands, we offer a 100% legal way to explore your mind with psilocybin. Access to expanded states of consciousness in a modern, comfortable, medically supervised context.


All our programs include a preparation and integration program. Preparation is key for maximising the potential of a beneficial psychedelic experience and integration is important for prolonging the benefits in well-being. We are dedicated to ensuring that our participants understand the unique ways that psilocybin can aid in healing and growth, the importance of set, setting, intentions, and personal practices.


Synthesis is committed to science-based data and contributing to research. To date we’ve collaborated with The Psychedelic Research Group of Imperial College London in a pilot study where we discovered that the biggest factors for a transformational psychedelic journey are: sense of safety, quality of intention, the absence of escapist behaviours and distractions, and the feeling of community - all important aspects that we safeguard. By attending Synthesis you get the opportunity to contribute to pioneering science and furthering the well-being of our planet.


Through our collaboration with the Psychedelic Research Group at Imperial College London, Synthesis is contributing to pioneering data. Even in healthy individuals, we found a 42.4% sustained reduction in depressive symptoms.


We designed your whole journey in order to reduce any anxiety or nervousness you might feel. From the sound experience to personalized care, every element is planned to ensure your optimal mindset and comfort in the setting, preparing you for your psychedelic experience with as little resistance as possible.


Your journey begins with an in-depth exploration call to fully understand your background and needs, so we can provide absolute clarity in the journey ahead and how to get the most out of your experience. Throughout the retreat, we cater to your individual needs by offering workshops for all levels and one-on-one consultations with our professionals, in order for you to go in prepared and process your experience to extract valuable life lessons.


You will receive lifetime access to our private community as part of your retreat commitment. This ever-evolving community offers access to professional support and networking as you continue the process of your own psychedelic journey and personal development.


The application procedure involves a thorough health check by our medical team to ensure your safety. Medical practitioners are present during the retreat.


We have a few different options:




The Lighthouse is a special and inspiring place to slow down, disconnect your mind from the outside world, and journey deep within yourself. Located a short 30 min drive from the city of Amsterdam or the airport, on a former dune in the middle of Zandvoort, you will find a home away from home, near the beach, a nature reserve, and the sea.

The Lighthouse is composed of 6 private apartments, each with access to a beautiful garden at the back, a sauna, a relaxation / yoga area (80m2) and a large shared kitchen. Designed by Osiris Hertman - the apartments have a unique character and are designed for you to relax and enjoy your space. Creating the perfect setting for a truly transformative experience on your Synthesis Retreat.


How to Start Your Journey:


Schedule your complimentary Exploration Call where you will speak 1:1 with a Synthesis team member. This is your time to dive deeper into your intentions, questions, hopes and potential concerns about the journey ahead.


With your safety as our priority, prior to your call, you complete a medical screener form that is reviewed by medical professionals to ensure your safety before, during and after your journey.


During your Exploration Call, you could be invited to attend a retreat and we will discuss the best options to suit your needs including dates and programs.


Prior to your retreat, you will receive all the practical information you need, as well as an invitation to your first group preparation call, where you will have the opportunity to meet and connect with your facilitators and fellow participants.


400+ people have embarked on a journey through Synthesis over the past year They happily share with you how it has impacted their lives


 “The experience has been nothing short of life changing. From the facilitators, to the people I shared the venue with, everyone was warm, caring, and accepting. The Synthesis team is doing amazing work, long may it continue. I can't wait to attend again!”

William, 37, Recruitment, UK

“It would be impossible for me to speak too highly of the benefits of undergoing the Synthesis psilocybin retreat. The guidance offered, in the in the weeks leading up to the retreat itself, through the care and commitment of the facilitators before, during and after the ceremony/experience, coupled with the offer of support and assistance, guarantees (to those who ensure they arrive with the right mindset) a successful outcome. I took away from my time in Amsterdam a foundation which I know I can continue to build on in the years to come.

My perception of the benefits I've gained have already been confirmed by those near and dear to me and already the benefits have extended beyond the merely personal into my deepest relationships. This has been one of the most truly transformative experiences I've ever undergone. It is without question unlike any of the other modalities I have undertaken over many years and clearly the one that to date has had the most significant impact in enabling me to understand who I am, why I have lived my life as I have to date and what I will now do with what of it remains.”


Stewart, 62, Insurance, Australia


“For those of us searching for meaning or redirection, Synthesis and its facilitators can help you self-guide to what is your higher calling or purpose.”


Lauren, 34, Accountant, USA


“I really appreciated the way the Synthesis team was informative, educational and to the point and at the same time sacred and ceremonial. Last but not least I appreciated how they were kept totally secular, that is important to me. What struck me as surprising was that the actual psychedelic journey was a much lesser piece of the overall experience than I had expected. I did expect the surrounding activities to be nice and interesting, but not that they would be essential to the experience and the possibility to learn from it in the way that they turned out to be.”


Jonah, 40, Teacher, Sweden


“I couldn't think of a better place for a psilocybin retreat. The Synthesis team is very loving and supportive, the building modern and beautiful, the food lovingly prepared. I am glad that I took part and I will come again.”

Marcel, 53, Teacher, Switzerland



“The Synthesis team is amazing, from the first email to the emotional goodbye hug they are top class every step of the way. Having been to many spiritual/development focused retreats (meditation, motivational speakers, etc) this was one of the most professionally run and knowledgeable I’ve ever been to. Also, as a complete novice to entheogens/psychedelics it was amazing to see how the retreat catered to those of all levels, helping a rookie like me feel very safe & secure while still keeping those with more experience really engaged! Lastly, they do a great job of curating groups of awesome people, while our group was very diverse there was no drama or issues. Amazing experience, people and team!”


Daniel, 27, Market Research & Analytics, Canada


"This retreat allowed me to explore areas in my life I had not been able to easily access. Everyone was professional and lovingly compassionate and caring. A beautiful experience."

Marion, 66, Psychotherapist, USA



Find out why our participants rate us 9.7/10


Frequently Asked Questions


About Synthesis

+ What is Synthesis?

Synthesis is pioneering transformative wellness to help you achieve wisdom-lessing, improved connections, lasting betterment in your mood, outlook on life, relationships, and overall mental wellbeing through medically-overseen, guided psychedelic experiences. We use a combination of Psilocybin truffles, evidence-based wellness programs, and the support of an interdisciplinary team of experienced guides to optimize your healing journey. Read more about us.

+ Who is Synthesis for?

Synthesis is for people who are looking for the best in mental health and wellness practices. We work with professionals of all walks of life and ages, from those who are new to expanded states of consciousness, as well as the highly experienced. Read more about who comes to Synthesis.

+ How does it work?

You begin by scheduling discovery call with your Synthesis guide to see if a Psilocybin retreat is right for you. Before your call, we will ask you some personal and medical data. Then, we’ll book your dates, send you your preparation information, and introduce you to your group and lead facilitator for your retreat. Book your call.

+ How much do your programs cost?

Our retreat types differ in time and value, and therefore in price. Please refer to the retreat pages for more information and price: Core 3-day retreat, Expansion 5-day retreat, Women’s leadership 5-day retreat, Private 3-day retreat. Please ask about our scholarship program.

+ Are there scholarships available?

We have scholarships available. Please ask for on your discovery call what is possible for you.

On Psilocybin

+ Are psilocybin truffles really safe?

According to recent studies, psilocybin mushrooms (which have the same active ingredient as truffles) are the safest drug currently known - safer than tobacco, cannabis, and alcohol. These substances are non-addictive, non-toxic, and, when taken within a structured setting under the guidance of medical professionals, hold little to no risk. Read more about psilocybin truffles.

+ What is Psilocybin?

Psilocybin, upon entering the body, is quickly metabolized into psilocin, which is responsible for the well-known psychedelic effects. Psilocin acts on serotonin at the 5-HT2A receptor, increasing the amount of serotonin available in the brain, and producing profound changes in perception, such as visual and auditory hallucinations, tactile perceptions (such as tingling or warmth), and synaesthesia (the merging of senses).

Users of psilocybin report entering a profound state of mind where the usual limits of consciousness are expanded. Realizations about the self and the universe may come to the forefront, and people will often describe feelings of unity, interconnectedness, and unconditional love. Studies have shown that psilocybin can induce a mystical experience and that this positively correlates with the benefits that users report following the trip.

+ What is the dosage used in the retreat?

We determine our dosage together with you during your 1-1 conversation. What we recommend varies, depending on your intentions, previous experience, your sensitivity to expanded states of consciousness, and your anxiety level on retreat. On average we use the clinical standard of 30mg/70kg of psilocybin and psilocin. When it is your first time, we recommend a slightly lower dose to get more comfortable with these states of consciousness. If you have more experience or a strong contemplative practice, we are open to provide much higher dosages.

The Synthesis Experience

+ Why the retreat model?

Studies have shown that the context of a group retreat and having experienced guides are essential ingredients to properly optimize for safety and getting the most out of a psychedelic experience. From years of retreat experience we know the value of this experience is rooted in the whole process, from being able to surrender fully because there is medical and professional support, to the meaningful relationships you will build with others.

+ How will the psychedelic sessions be set up?

We provide a comfortable indoor space with mattresses to lay down on, eye shades, and profound music. There are also creative spaces inside and outside to explore. In creating an optimal environment for your psychedelic experience, we combine ceremonial aspects rooted in age-old tradition with modern approaches that have proven, in scientific research, to be effective at facilitating a deep, meaningful experience.

+ Is there any preparation and integration work included with the retreats?

Upon arrival, guests participate in both group and individual workshops to help prepare them for the psilocybin ceremony. On the day of the ceremony, guests participate in a breathwork session and are carefully supported by experienced practitioners, including an on-site medic as they experience psilocybin in a therapeutic context. After the ceremony, guests participate in group and individual workshops focused on integration before customers return home. Additional preparation and integration support is also offered digitally outside of in-person retreat dates.

+ What is the typical age of people attending retreats at Synthesis?

You are over the age of 18 You take a mature approach to your work and relationships You are looking for an experience designed to catalyze deeper self-understanding and personal growth You have a developing interest in the safe and responsible use of psychedelics. See more: 'Is Synthesis right for me?

+ Will my personal information be confidential?

We keep all personal information confidential, none of it will be shared with third parties.

+ Do you offer 1-to-1 guided sessions if I prefer to do this in private?

Yes, we do! Please see our private retreat offer for more details. We also offer 1-to-1 preparation and integration coaching as an option during our group retreats, for an additional fee.

+ Can I do more than one retreat?

Yes, you can. A second retreat can be a quite different experience, certainly not just a repetition. In case it‘s your second overall psychedelic experience, many people tend to be even better prepared and relaxed as there is a familiarity that allows them to let go or direct their experience even more. For experienced psychonauts on the other hand, each experience can have its own focus or topic, exploring different aspects.


Life is too short to (live in the past). It’s time to get out of your own way.

Talk about the DMN. 

The world needs you -

It’s time to go on a journey. To step into the unknown 

Feelings of stress, anxiety and fear are holding you back. Through your hunger and desire to change, you’ve tried a few things. You may have been working through some issues for a while, tried all the things, and while you might experience short term success, time passes and you find yourself back where you didn’t want to be. 

There is a reason that the recent findings of studies have sent the pharmaceutical industry into a frenzy. The world is just waking up to the ----- that scientists have known all along.

These profound positive changes in people’s perspective and in some cases, personality  possible. 

Psychedelics could ‘change your mind’

Research is showing that taking psychedelics can significantly change personality traits that usually stay stagnant in adults. Changes that people had never thought possible.

And here’s why.

We understand the power of plant medicine and the need to create a safe, legal and supportive environment to ensure that those who are ready to pioneer and pave a new life...professionals like you, and we have designed it for you.

The pioneers, creators of their own destiny. This retreat is for you if you are ready to experience something truly life changing. 

Research has shown

We believe that everyone should have safe, access to the power of psychedelics 

Things are possible now that weren’t possible a week ago
— Mary

 Join over 500 people who have transformed their lives at a Synthesis Retreat