A legal psilocybin retreat – Synthesis

Synthesis is a safe, legal, and modern psychedelic retreat utilizing psilocybin truffles for creative breakthroughs, personal growth, and spiritual development. Click below to join us on our next retreat!

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Personal & Professional Breakthroughs

Steve Jobs called it one of the most profound experiences of his life.

Tim Ferriss, best-selling author and tech entrepreneur, has said that all the billionaires he knows, with few exceptions, take this journey on a regular basis.

And Plato formed his foundational beliefs by utilizing the psychedelic experience, thus setting the groundwork for all of Western philosophy. 

Why does this matter for you? Well, we’ve created a retreat around this very experience - one of the most meaningful, profound experiences an individual can have - and made it available to you at our retreat center just outside of Amsterdam.

At Synthesis we offer personal transformation retreats for forward-thinking individuals who want to access the psychedelic state using psilocybin truffles, the active component of magic mushrooms within a modern, legal, and medically supervised context . 

When used within a structured framework, psychedelics are one of the only modalities that, within hours of ingestion, can create a dynamic, impactful shift in consciousness.



How we do it

First off, we administer the truffles in a way to reduce physical discomfort and nausea. Then, taking into consideration your intention, sensitivity, and previous experience, we optimize the best dosage for you. Finally, we integrate the latest findings and best practices from the psychedelic research community to ensure your experience is as profound and effective as possible.

In committing to this experience, you will be a pioneer in your own right, joining a specially curated list of attendees who are contributing to the next conscious evolution of humanity in a significant way.

Are you ready to join us on this journey?



The Synthesis experience

By joining our retreat, you will:

  • Have a legally sanctioned, professionally guided, optimally comfortable, moderate-to-high-dose psilocybin experience in a beautiful, modern setting. (Read more about psilocybin and psilocin, the psychoactive components in magic truffles and magic mushrooms

  • Catalyze breakthroughs in your self-understanding to live a more meaningful, purpose-driven life

  • Further develop your educational framework on the use of psychedelic substances, empowering you to use these transformational tools in a responsible, intentional manner

  • Connect with other successful, motivated individuals who have a deep interest in the emerging topic of psychedelic use

  • Contribute to nascent psychedelic research, helping to pave the future path for best practices in retreat settings

But Synthesis isn't just about the retreat experience itself. It is also about the transformation that will be with you for the rest of your life.

One of the most important aspects of any meaningful psychedelic experience is the integration process. You will learn how to integrate your profound insights through our integration workshop.

Then, once you go back home, you will receive lifetime access to the SYNTHESIS ‘Inner Circle’ as part of your retreat commitment.This will be an ever-evolving group that will provide professional support and networking as you continue the process of your own psychedelic journey and personal development.

We believe our ‘Inner Circle’ is one of the most valuable aspects of our particular retreat. It is a lifetime opportunity to meet and deeply connect with other ambitious, talented, and inspiring participants, who may also go on to become fruitful collaborators in your professional pursuits.


The Synthesis team is amazing, from the first email to the emotional goodbye hug they are top class every step of the way. Having been to many spiritual/development focused retreats (meditation, motivational speakers, etc) this was one of the most professionally run and knowledgeable I’ve ever been to. Also, as a complete novice to entheogens/psychedelics it was amazing to see how the retreat catered to those of all levels, helping a rookie like me feel very safe & secure while still keeping those with more experience really engaged! Lastly, they do a great job of curating groups of awesome people, while our group was very diverse there was no drama or issues. Amazing experience, people and team!!
— DANIEL, 27, Market Research & Analytics, Canada

Upcoming retreat dates

We currently offer 3-day retreats for 12 to 16 attendees.

For more details about the general retreat format and the ceremony, continue here.


The Lighthouse, about 40 minutes from Amsterdam center.

To see photos of the gorgeous venue, the healthy and delicious catering, plus the stylish apartments, continue here.


The price per person for the full retreat, including 2 nights of accommodation and all meals is $2,000 including 21% VAT.

For information about the exclusive private retreat please continue here.

Retreat dates

The following dates are scheduled at this time. Select a date to continue to the application form.



3-Day Retreat

Your facilitators: Natasja Pelgrom (lead facilitator), Tessa Van de Ven (assistant facilitator).


3-Day Retreat

Your facilitators: Natasja Pelgrom (lead facilitator), Adam Rice (co-lead facilitator), Daan Keiman (assistant facilitator).


3-Day Retreat

Your facilitators: Natasja Pelgrom (lead facilitator), Daan Keiman (co-lead facilitator).


3-Day Retreat

Your facilitators: Daan Keiman (lead facilitator), Alex Pardhy (co-lead facilitator).


3-Day Retreat

Your facilitators: Daan Keiman (lead facilitator), Tessa Van de Ven (co-lead facilitator), Adam Rice (assistant facilitator).


3-Day Retreat

Your facilitators: Natasja Pelgrom (lead facilitator), Daan Keiman (co-lead facilitator), Adam Rice (assistant facilitator).


3-Day Retreat

Your facilitators: Adam Rice (co-lead facilitator), Tessa Van de Ven (assistant facilitator).


3-Day Retreat

Your facilitators: Daan Keiman (lead facilitator), Adam Rice (co-lead facilitator).


3-Day Retreat

Your facilitators: Adam Rice (lead facilitator).


Women’s Leadership 5-Day Retreat

Your facilitators: Natasja Pelgrom (lead facilitator), Rachel Aidan (co-lead facilitator), Tessa Van de Ven (assistant facilitator).


If you are interested in attending at a later time, please continue to our application here .


Thank you again for organising such an amazing event and making it so rewarding for me and the other participants. […]
— Raphael, 43, from Switzerland
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I feel that I made one of the best decisions of my life by deciding to attend the Synthesis retreat. My life has improved on numerous fronts and I have adopted new practices (e.g., daily meditation and free-flow writing) to sustain my new outlook on life. […]
— Jon, 27, from USA
→ read more

Your 3-Day Synthesis Retreat

We offer an exclusive 3-day retreat in Amsterdam for individuals who want to utilize moderate-to-high doses of psilocybin truffles to catalyze creative breakthroughs, deepen self-understanding, and feel ready to make their next big ‘leap’ in life.

This is a legal opportunity to take psychedelics in a safe, intentional and expertly-guided setting, geared to facilitating positive outcomes like heightened creativity, clarity on next steps in your life, and general personal development.

To create your experience, we will carefully modulate the following six conditions, each of which plays an essential role in every psychedelic journey:

  • Set. The mental attitude of a would-be psychedelic voyager

  • Setting. The surroundings in which a psychedelic substance is ingested

  • Guide. A person experienced with non-ordinary states of consciousness who helps to mitigate challenges and channel insights. (Read more about our team of coaches.)

  • Substance. The type and quantity of psychedelic agent; in this case, psilocybin, from truffles

  • Session. The entirety of a psychedelic trip, including all activities and rituals

  • Situation. the environment, people, and culture from which a person comes to a session and returns to afterwards

When these elements are not carefully considered, and psychedelics are not used in a safe, supportive, and structured setting, many of their potential benefits may not be experienced. That’s why we pay such close attention to crafting the environment that we create for your experience. We understand that working with psychedelics can be intimidating; the nurturing environment we create will help to allay any concerns that may come up for you.

With due respect to the powerful nature of psychedelic experiences, and the strong impact that the presence of the others sharing the space can have on your trip, we limit each workshop to 12-16 carefully selected participants. Before joining us at Synthesis for your 3-day retreat experience, please complete our compulsory application form, which will be assessed by our guides and medical care team.

Day 1: Preparation

After arriving at The Lighthouse, the main focus of your first day will be 1-on-1 conversations with your lead facilitators to help clarify your intentions during the retreat and calibrate your dose level. We will also discuss whether you want to optimize your experience for creativity on a professional level, for personal development or are seeking a mystical experience.

11:30 - Arrival - Transfer from AMS

13:30 - Welcome Circle

14:00 - Welcome Lunch

15:00 - Flight Instructions

16:30 - 1 on 1 Conversations

19:00 - Dinner

20:00 - Q&A plus Activity

Day 2: Ceremony

On the second day of the retreat, you will participate in the ceremony, consuming the psilocybin truffles at either a low, moderate, or high dose. You will be fully prepared and comfortable in a setting perfectly optimized for your needs, allowing you to make the most of your psychedelic experience.

8:00 - Breakfast

9:30 - Breathwork

13:00 - Psilocybin Ceremony

21:00 - Dinner

Day 3: Workshop

The retreat’s final day centers on the integration workshop. You will discuss and receive guidance on how to process your experience and integrate it into your life going forward. This will allow you to bring your newfound insights back with you and make concrete, meaningful changes.

8:30 - Breakfast

9:30 - Integration Part 1

11.00 - 1 on 1 Conversations

12:30 - Closing lunch

13:30 - 1 on 1 conversations

14:30 - Integration Part 2, Closing Circle

16.00 - Departure - Transfer to AMS


The price per person for the full retreat, including 2 nights of accommodation and all meals is $2,000 including 21% VAT.

For information about the exclusive private retreat please continue here.



Watch this four minute video to understand the impact of Synthesis on previous attendees:


Is Synthesis Right for You?

Synthesis is great for you if:

  • You want to connect with ‘like-minded’ individuals and start to build a community around you of people interested in the modern, responsible use of psychedelics.

  • You’ve been stuck on a major professional or personal problem for an extended period of time and are looking for creative inspiration.

  • You want to explore the outer reaches of your consciousness, unlocking aspects of your mind that have yet to be accessed.

  • You’re curious about the utility of psychedelics and want to do them in a safe, legal, and structured setting.

  • You feel like there’s a psychological blockage preventing you from reaching that ‘next stage’ in your professional or personal development.

  • You want to press reset on your mind, and break out of your tired, habituated thought patterns.

  • You’re open to the potential value of psychedelics but haven’t found the right time and place yet.

  • You’re intent on being your ‘best self’ and you want to learn how to utilize psychedelics to accelerate the process of personal development.

Synthesis is not for you if:

  • You have a clinical diagnosis of depression, bipolar, borderline, PTSD, or schizophrenia.

  • You have a family history of schizophrenia or psychosis.

  • Currently prescribed to anti-depressant medications (please contact us if you want to be notified when medical spots open up).

  • You are just looking to get high and have fun.


Despite the exciting potential for the clinical use of psychedelics, Synthesis is not a retreat for people looking to experience psychedelics to treat a specific clinical condition. By going through the application process, you accept that we can not accept individuals on prescription medication for mental disorders, there is no clinical motivation for your participation, and that Synthesis Retreat will not be held accountable for any issues that arise from your Synthesis Experience.


Who will facilitate the sessions and what are their qualifications?

Please refer to the about page for information on facilitators and their qualifications. Please feel free to contact us if you have any further questions.

How will the psychedelic sessions be set up?

We provide a comfortable indoor space with mattresses to lay down on, eye shades, and profound music. In creating an optimal environment for your psychedelic experience, we combine ceremonial aspects rooted in age-old tradition with modern approaches that have proven, in scientific research, to be effective at facilitating a deep, meaningful experience.

Why should I invest in this experience if I can take mushrooms home?

We believe the context of a group retreat and having experienced guides are essential ingredients to properly optimize for safety and getting the most out of a psychedelic experience. From years of retreat experience we know the value of this experience is rooted in the relationships you will build.

Can I do more than one retreat?

Yes, you can. A second retreat can be a quite different experience, certainly not just a repetition. In case it‘s your second overall psychedelic experience, many people tend to be even better prepared and relaxed as there is a familiarity which allows them to let go or direct their experience even more. For experienced psychonauts on the other hand, each experience can have its own focus or topic, exploring different aspects.

Is there any prep or post work included with the retreats?

Prior to the 3-day retreat, you will have a 1-2 hour group video call with your facilitators to discuss the retreat. More preparation documents will be sent over nearing your retreat date. During the retreat, you will have two 30-minute private conversations to discuss anything that might come up. We will always be available for any assistance post-retreat.

Are psilocybin truffles safe?

According to recent studies, psilocybin mushrooms (which have the same active ingredient as truffles) are the safest drug currently available - safer than tobacco, cannabis, and alcohol. These substances are non-addictive, non-toxic, and, when taken within a structured setting, have little to no risk.

Where can I learn more about psilocybin truffles?

To get more information about psilocybin truffles, please read through this Essential Guide on Psilocybin Mushrooms.

Here is a brief overview of the legal status of psilocybin truffles in the Netherlands.

What are the long term risks associated with psilocybin truffles?

As long as you do not have a pre-disposition to psychosis or schizophrenia, and are currently not prescribed any there are little to no long-term risks associated with psilocybin truffles.

Will my personal information be confidential?

We keep all personal information confidential, none of it will be shared with third parties.

I’m excited about this opportunity but nervous about trying psychedelics for the first time. Do you have further resources I can check out?

The best beginning resource is The Third Wave, a website dedicated to psychedelic literacy and education.

Can I opt out for the research?

Yes, you may opt out at any time, participating with our research is not mandatory. Part of these retreats is to discover the potential of psychedelics on human development and to improve the integration of these substances in your life. If you do choose to participate, all of your data will be held strictly anonymous.

Can two people submit a joint application to sign up?

Two people (i.e. a couple, or friends) can sign up for the same retreat, but we will need an individual application per person.

If you both mention your partner during the application, we will make it a priority to place you both on the same retreat. You will be able to share a room during your stay, if requested.

During the retreat, you will each have your own guide for 1-on-1 sessions. You will have the option of being together for your psilocybin experience. We will explain the pros and cons of this to you both beforehand, so that you can make an informed decision about the best way for you to maximize your experience at Synthesis.

Do you offer 1-to-1 guided sessions if I prefer to do this in private?

Yes, we do! Please see our private retreat offer for more details. We also offer 1-to-1 preparation and integration coaching as an option during our group retreats, for an additional fee.

What is the typical age bracket of people attending retreats at Synthesis?

  • You are over the age of 18
  • You take a mature approach to your work and relationships
  • You are looking for an experience designed to catalyze deeper self-understanding and personal growth
  • You have a developing interest in the safe and responsible use of psychedelics. See more: 'Is Synthesis right for me?

How is the psilocybin truffle experience offered at Synthesis different from other kinds of psychedelic retreat experiences, for example, attending an ayahuasca ceremony in Peru?

There are a great many different types of psychedelic retreat. Synthesis is a new model of retreat, based in the Netherlands, which uses psilocybin truffles. The experience that you will have at Synthesis is in many respects different from the kind of experience that you would have at a traditional shamanic ayahuasca or peyote ceremony. When you are doing your preliminary research into what kind of psychedelic retreat experience might be most appropriate for you, there are a great many different aspects of the retreat to consider, each of which has a crucial impact on the overall experience that you will have. These include:

The retreat location. This will also affect the legality of taking psychedelics, and the particular cultural contexts that may be drawn on.

  • Synthesis has been designed to allow people to have a psychedelic experience in luxury accommodation in a developed country (with hot meals, running water and clean sheets, etc.)
  • Ayahuasca retreat centers in South America typically provide much more basic accommodation, equipping participants with essentials such as food, water, and bedding, often in partially outdoor/camping conditions. To give you an accurate flavor of this type of experience without over-generalizing, insect repellent is a must.

The format of the ceremony itself. This depends on which traditions it will be based on, and what language(s) will be spoken by the facilitators.

  • Psilocybin truffles have a short duration (ideal for first-time psychedelic users), and each participant receives individual attention from facilitators.
  • Ayahuasca has a much longer duration and is typically taken overnight in a large-scale ceremony with music. Buckets are provided to accommodate nausea and vomiting which most people experience.

The group dynamics. Factors like the group size, typical age range, and whether there is a screening process, will all affect the overall group dynamic.

  • At Synthesis, the psilocybin ceremony takes place in a small group, with a maximum size of 16 participants, with an individual focus from the guides on each person’s specific needs, as detailed in their application. Our medical/health and safety protocols draw on gold-standard practices used in clinical research into psilocybin, which has an illustrious 70+ year history.
  • In ayahuasca ceremonies in developing countries, group sizes can be 20-30+. The emphasis placed on modern health and safety standards may be minimal.

Preparation and integration. Find out how extensive this will be, what activities it is likely to consist of, and consider whether these feel right for you.

  • At Synthesis the preparation and integration activities devised by our guides are designed to lend a helping hand at every stage of your journey. Participants begin preparing emotionally for their journey two weeks beforehand, with materials provided in order to help with intention setting and logging their thoughts in the run-up, as well as one-on-one consultations with facilitators and groupwork surrounding the psilocybin ceremony itself.
  • The preparation and integration guidelines will be different at every retreat, so find out what kinds of activities the particular ayahuasca retreat you are considering offers in this regard. Always ensure that your travel plans allow you to fully participate in the retreat’s preparation and integration activities bookending the ceremony itself.

While it is important to consider all of the above elements before making a decision, the most crucial aspect of all to consider is:

The substance used, and whether the kind of trip it produces is right for you. Before planning to take any kind of psychedelic substance, research its unique palette of psychological effects.

Truffles produce an experience which is relatively short-lasting compared to other natural psychedelics, and the method of administration used at Synthesis is designed to the minimize any nausea that may be present during its onset.

Ayahuasca is a long-lasting psychedelic plant brew produced from plants that grow in the Amazon, and has been used for millennia by indigenous groups in ceremonial contexts to induce visionary states.

Although the kind of journey that ayahuasca could take you on will vary considerably depending on the structure and nature of the ceremony, all ayahuasca experiences must be preceded and followed by a strict dietary regimen, often lasting several weeks (known as the dieta) and a period of sexual abstinence, in order to prepare the body to consume the brew safely. (The specifics of these practices can vary greatly between different ayahuasca retreat centers. All responsibly run retreats will provide their own guidelines and explanations of these.) In practical terms, this is the most distinctive point of contrast between ayahuasca and psilocybin, which can be consumed safely without this level of physical preparation.

Find out what you can expect mentally and physically during the trip, including its duration, and any necessary prep and aftercare practices. Learning about your chosen substance in advance will help you to get the best out of your participation. The information you find out as you consider taking this exciting new direction will also equip you to decide whether any given retreat you might be considering offers the format and structure in which you would most like to experience that particular psychedelic. For more information about the psychedelic agent used at Synthesis, consult our resources on truffles, and their active ingredient, psilocybin.


Next Steps


1. Apply

Please complete your application (click here). Be as truthful and precise as possible. We will follow up on all answers and any questions you might have during our call. 

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2. Get Informed

Schedule a free application call with one of our experts to answer any questions you may have before reserving your spot with a deposit. The call will last approximately 20 minutes.


3. Come to Amsterdam

Once the event draws nearer, we will send you all the practical information you need. We will also ask you to dive deep into a few exercises to optimally prepare your mind and body.

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