Synthesis is a legal, medically supervised, psilocybin retreat center for professionals to experience personal growth, emotional breakthroughs and spiritual development
Our retreats are centered around the ceremonial use of high-dose, legal psilocybin truffles to catalyze this transformation, but the retreat experience goes far beyond that.
We have curated an expert team of facilitators, therapists, meditation and breathwork instructors, and designed an experience that blends the best of ancient wisdom, with cutting edge science.
You’ll be joining a community of over 500 pioneering professionals, who have trusted us to guide them through their self-exploration and ultimately, growth.
Our passion for stewarding the psychedelic renaissance has led us to create a retreat program that our participants are reporting as one of the most impactful experiences of their lives.
While everyone’s experience is unique, here are some of the incredible results that our study has shown:
INCREASED SENSE OF WELL-BEING
The national average of positive mental health is 50.7. Four weeks after a Synthesis retreat, our participants go from 48.6 to 54.5. A tremendous 10% lasting increase.
INCREASED POSITIVE MOOD
Synthesis participants report better sleep, decreased rumination, positive mood, improved concentration, and healthier eating habits.
The degree of connection that each participant experienced to themselves, others, and nature, more than doubled after Synthesis, an increase of 118% About half of participants had a full mystical experience.
REDUCED STRESS & WORRY
The degree of fear and stress reported by participants decreased by and remained lowered by 13.8%.
*Data was collected and analysed independently in participation with Imperial College London. Baseline was two weeks before a Synthesis retreat and during. Follow up was two and four weeks after. Data and analysis can be found here.
Ready to start your journey?
The Synthesis Experience
Synthesis is leading a movement to transform the way people approach emotional, cognitive, and spiritual well-being, through safe and legal psilocybin experiences. Our retreat model represents a fusion of modern science, therapeutic modalities, and wisdom-traditions proven to catalyze deep psychological wellness and, meaningful change.
We have strategically partnered with Psychedelic Research Group of Imperial College London to contribute to the emergence of psychedelic science and ensure that our programs are as effective and scientifically informed as possible.
Our team of medical professionals perform comprehensive medical screenings for all applicants in order to identify any personal health risks, ensuring the safety of all of our participants.
The Synthesis Retreat Team consists of experienced professionals; trained in the best practices used in clinical trials, they have prepared and guided hundreds of participants safely through the full variety of psychedelic experiences.
Through our collaboration with the Psychedelic Research Group at Imperial College London, Synthesis is contributing to pioneering data. Even in healthy individuals, we found a 42.4% sustained reduction in depressive symptoms.
More than just a trip
We will guide you through our carefully designed psilocybin journey to experience the full potential of psychedelics. Lying down comfortably with your eyes gently covered, we will provide you with the best way to consume the psilocybin truffles to minimize nausea, letting yourself be guided through an amazing sound experience, knowing you are safe and supported.
In-depth Exploration Call
Individual Health Screening
Private 1:1 Coaching
Carefully Designed Set & Setting
Meditation & Breathwork
Ceremonial Psilocybin Experiences
Access to Additional
Private Inner Circle
In committing to this experience, you will be a pioneer in your own right, joining a specially curated list of attendees who are contributing to the next conscious evolution of humanity in a significant way.
Your Experience could Include:
Mystical states of consciousness
Overcoming destructive attachments
Deep and lasting sense of connection
Remembering meaningful memories
Challenging and confronting visions
Processing childhood experiences
Synesthesia — see sounds
Experiences of intense love and bliss
Letting go of suppressed feelings
Enhanced self-acceptance and compassion
Heightened states of creativity
*While there are no guarantees as to what kind of journey you will have - these are the most-commonly known types of psychedelic experiences.
How To Start Your Journey
1. Book Your Exploration Call
Schedule your complimentary Exploration Call where you will speak 1:1 with a Synthesis team member. This is your time to dive deeper into your intentions, questions, hopes and potential concerns about the journey ahead.
2. Complete Medical Screener
With your safety as our priority, prior to your call, you complete a medical screener form that is reviewed by medical professionals to ensure your safety before, during and after your journey.
3. Invitation To Attend
During your Exploration Call, you could be invited to attend a retreat and we will discuss the best options to suit your needs including dates and programs.
4. Prepare for your journey
Prior to your retreat, you will receive all the practical information you need, as well as an invitation to your first group preparation call, where you will have the opportunity to meet and connect with your facilitators and fellow participants.
The Lighthouse: A House Of Well Being
Located in a quiet seaside village just minutes outside of Amsterdam, The Lighthouse is beautifully hundred year old renovated church. Created with love, it is hard to explain the magic of the space, it really has to be experienced to be appreciated.
Each guest is welcomed to their private apartment with access to soothing gardens all around the property, plenty of private and communal spaces for you to explore on your journey, and of course, our sauna, and private yoga space. Our in house chef prepares delicious, healthy vegan meals and caters to any special dietary needs that are guests may have.
Choose Your Journey
Expansion by Synthesis
Our most comprehensive program, Expansion is a complete 7-week program designed for deep transformations. More than just a psilocybin ceremony, you will use this window of plasticity to grow your presence, self-acceptance, focus, and expand your range of states of consciousness in your daily life.
Core by Synthesis
Our standard 3-day retreat near Amsterdam in which you experience one dose of utilize moderate-to-high doses of psilocybin truffles to catalyze emotional breakthroughs and deepen self-understanding.
Women’s Leadership Retreat
Leadership is born from the relationship we have with ourselves; it is not a job title, it is a decision. We believe that true leadership is something that all women can access, with the right tools. During this five-day wellness retreat, made by women for women, you will relax, explore, learn, discover, breathe, heal, recharge and reach a state of alignment with your past, present and future selves, and the world around you.
Synthesis offers private retreats, an opportunity to work with two facilitators privately instead of participating in our larger group retreat model. The private retreat format offers participants the ability to customize their ceremony, tailoring the individual needs to maximize the transformational potential of their experience. Click below to see if this retreat is right for you.
Here's What You Need To Know
Synthesis: Legal Psilocybin Experiences
Based in the Netherlands, we offer a 100% legal way to explore your mind with psilocybin. Access to expanded states of consciousness in a modern, comfortable, medically supervised context.
Contributing to Science
Synthesis is committed to science-based data and contributing to research. To date we’ve collaborated with The Psychedelic Research Group of Imperial College London in a pilot study where we discovered that the biggest factors for a transformational psychedelic journey are: sense of safety, quality of intention, the absence of escapist behaviours and distractions, and the feeling of community - all important aspects that we safeguard. By attending Synthesis you get the opportunity to contribute to pioneering science and furthering the well-being of our planet.
Your journey begins with an in-depth exploration call to fully understand your background and needs, so we can provide absolute clarity in the journey ahead and how to get the most out of your experience. Throughout the retreat, we cater to your individual needs by offering workshops for all levels and one-on-one consultations with our professionals, in order for you to go in prepared and process your experience to extract valuable life lessons.
The application procedure involves a thorough health check by our medical team to ensure your safety. Medical practitioners are present during the retreat.
Preparation & Integration
All our programs include a preparation and integration program. Preparation is key for maximising the potential of a beneficial psychedelic experience and integration is important for prolonging the benefits in well-being. We are dedicated to ensuring that our participants understand the unique ways that psilocybin can aid in healing and growth, the importance of set, setting, intentions, and personal practices.
Set & Setting
We designed your whole journey in order to reduce any anxiety or nervousness you might feel. From the sound experience to personalized care, every element is planned to ensure your optimal mindset and comfort in the setting, preparing you for your psychedelic experience with as little resistance as possible.
You will receive lifetime access to our private community as part of your retreat commitment. This ever-evolving community offers access to professional support and networking as you continue the process of your own psychedelic journey and personal development.
OCT 25-27 core 3-day retreat
NOV 1-3 Core 3-day retreat
NOV 15-17 Core 3-day retreat
NOV 7-11 Expansion 5-day Retreat
NOV 22-24 Core 3-day retreat
As Seen In Media:
400+ people have embarked on a journey through Synthesis over the past year — They happily share with you how it has impacted their lives
“The experience has been nothing short of life changing. From the facilitators, to the people I shared the venue with, everyone was warm, caring, and accepting. The Synthesis team is doing amazing work, long may it continue. I can't wait to attend again!”
— William, 37, Recruitment, UK
“It would be impossible for me to speak too highly of the benefits of undergoing the Synthesis psilocybin retreat. The guidance offered, in the in the weeks leading up to the retreat itself, through the care and commitment of the facilitators before, during and after the ceremony/experience, coupled with the offer of support and assistance, guarantees (to those who ensure they arrive with the right mindset) a successful outcome. I took away from my time in Amsterdam a foundation which I know I can continue to build on in the years to come.
My perception of the benefits I've gained have already been confirmed by those near and dear to me and already the benefits have extended beyond the merely personal into my deepest relationships. This has been one of the most truly transformative experiences I've ever undergone. It is without question unlike any of the other modalities I have undertaken over many years and clearly the one that to date has had the most significant impact in enabling me to understand who I am, why I have lived my life as I have to date and what I will now do with what of it remains.”
— Stewart, 62, Insurance, Australia
“For those of us searching for meaning or redirection, Synthesis and its facilitators can help you self-guide to what is your higher calling or purpose.”
— Lauren, 34, Accountant, USA
“I really appreciated the way the Synthesis team was informative, educational and to the point and at the same time sacred and ceremonial. Last but not least I appreciated how they were kept totally secular, that is important to me. What struck me as surprising was that the actual psychedelic journey was a much lesser piece of the overall experience than I had expected. I did expect the surrounding activities to be nice and interesting, but not that they would be essential to the experience and the possibility to learn from it in the way that they turned out to be.”
— Jonah, 40, Teacher, Sweden
“I couldn't think of a better place for a psilocybin retreat. The Synthesis team is very loving and supportive, the building modern and beautiful, the food lovingly prepared. I am glad that I took part and I will come again.”
— Marcel, 53, Teacher, Switzerland
“The Synthesis team is amazing, from the first email to the emotional goodbye hug they are top class every step of the way. Having been to many spiritual/development focused retreats (meditation, motivational speakers, etc) this was one of the most professionally run and knowledgeable I’ve ever been to. Also, as a complete novice to entheogens/psychedelics it was amazing to see how the retreat catered to those of all levels, helping a rookie like me feel very safe & secure while still keeping those with more experience really engaged! Lastly, they do a great job of curating groups of awesome people, while our group was very diverse there was no drama or issues. Amazing experience, people and team!”
— Daniel, 27, Market Research & Analytics, Canada
"This retreat allowed me to explore areas in my life I had not been able to easily access. Everyone was professional and lovingly compassionate and caring. A beautiful experience."
— Marion, 66, Psychotherapist, USA
Find out why our participants rate us 9.7/10
Frequently Asked Questions
+ What is Synthesis?
Synthesis is pioneering transformative wellness to help you achieve wisdom-lessing, improved connections, lasting betterment in your mood, outlook on life, relationships, and overall mental wellbeing through medically-overseen, guided psychedelic experiences. We use a combination of Psilocybin truffles, evidence-based wellness programs, and the support of an interdisciplinary team of experienced guides to optimize your healing journey. Read more about us.
+ Who is Synthesis for?
Synthesis is for people who are looking for the best in mental health and wellness practices. We work with professionals of all walks of life and ages, from those who are new to expanded states of consciousness, as well as the highly experienced. Read more about who comes to Synthesis.
+ How does it work?
You begin by scheduling discovery call with your Synthesis guide to see if a Psilocybin retreat is right for you. Before your call, we will ask you some personal and medical data. Then, we’ll book your dates, send you your preparation information, and introduce you to your group and lead facilitator for your retreat. Book your call.
+ How much do your programs cost?
Our retreat types differ in time and value, and therefore in price.
Please ask about our scholarship program.
+ Are there scholarships available?
We have scholarships available. Please ask for on your exploration call what is possible for you.
+ Are psilocybin truffles really safe?
According to recent studies, psilocybin mushrooms (which have the same active ingredient as truffles) are the safest drug currently known - safer than tobacco, cannabis, and alcohol. These substances are non-addictive, non-toxic, and, when taken within a structured setting under the guidance of medical professionals, hold little to no risk. Read more about psilocybin truffles.
+ What is Psilocybin?
Psilocybin, upon entering the body, is quickly metabolized into psilocin, which is responsible for the well-known psychedelic effects. Psilocin acts on serotonin at the 5-HT2A receptor, increasing the amount of serotonin available in the brain, and producing profound changes in perception, such as visual and auditory hallucinations, tactile perceptions (such as tingling or warmth), and synaesthesia (the merging of senses).
Users of psilocybin report entering a profound state of mind where the usual limits of consciousness are expanded. Realizations about the self and the universe may come to the forefront, and people will often describe feelings of unity, interconnectedness, and unconditional love. Studies have shown that psilocybin can induce a mystical experience and that this positively correlates with the benefits that users report following the trip.
+ What is the dosage used in the retreat?
We determine our dosage together with you during your 1-1 conversation. What we recommend varies, depending on your intentions, previous experience, your sensitivity to expanded states of consciousness, and your anxiety level on retreat. On average we use the clinical standard of 30mg/70kg of psilocybin and psilocin. When it is your first time, we recommend a slightly lower dose to get more comfortable with these states of consciousness. If you have more experience or a strong contemplative practice, we are open to provide much higher dosages.
The Synthesis Experience
+ How do I book directly?
We would like to make sure you have all your questions answered and trust a Synthesis retreat is right for you. That is why the first step towards joining a retreat is to book an exploration call with us. During this call, we'll explore your intentions, your questions and any concerns you might have. We'll also share more about our programs and explore if we are a good fit.
However, if there is a reason you do wish to attend the call, or would like to make an urgent booking, here is what to do:
Click, BOOK A CALL and follow the process outlined. While you pick your date and time, complete a few questions to help us personalize your experience.
Next, complete the medical screening process, and if approved, you will receive an email from us confirning your call. To bypass the exploration call stage simply reply to that email (or email us directly at email@example.com) and indicate the reason for not attending the call and the dates and program you would like to attend. We will correspond through email with you.
+ What if I'm not medically approved?
In order for us to accurately assess your suitability and safety for a psilocybin journey, as well as to provide you with a personalized experience during your retreat, we would love to get to know you better first and see whether Synthesis is right for you.
If you screener identifies anything that requires a closer look by our medical team, we will wait until we get clearance from them. In the mean time, we will postpone your Exploration Call while we work with you on your case.
There are three possible outcomes of this review:
- Your Health Screener is approved and you are invited to reschedule your Exploration Call
- To get a better understanding of your condition, we may request some more information from you. This may be over email or in the form of a brief call.
- If we don't feel as though we can support you safely through your psilocybin experience, we may decline your application and therefore your Exploration Call (if this happens, we will send you an email with further details) Throughout this entire process, we handle your information with the utmost care and consideration for your confidentiality.
We appreciate this may feel like a roadblock and we want you to know that our medical team will work with you, with your best interests at heart, to determine the best course of action. Thank you for your patience and understanding. Your safety is our primary concern.
+ Why the retreat model?
Studies have shown that the context of a group retreat and having experienced guides are essential ingredients to properly optimize for safety and getting the most out of a psychedelic experience. From years of retreat experience we know the value of this experience is rooted in the whole process, from being able to surrender fully because there is medical and professional support, to the meaningful relationships you will build with others.
+ How will the psychedelic sessions be set up?
We provide a comfortable indoor space with mattresses to lay down on, eye shades, and profound music. There are also creative spaces inside and outside to explore. In creating an optimal environment for your psychedelic experience, we combine ceremonial aspects rooted in age-old tradition with modern approaches that have proven, in scientific research, to be effective at facilitating a deep, meaningful experience.
+ Is there any preparation and integration work included with the retreats?
Upon arrival, guests participate in both group and individual workshops to help prepare them for the psilocybin ceremony. On the day of the ceremony, guests participate in a breathwork session and are carefully supported by experienced practitioners, including an on-site medic as they experience psilocybin in a therapeutic context. After the ceremony, guests participate in group and individual workshops focused on integration before customers return home. Additional preparation and integration support is also offered digitally outside of in-person retreat dates.
+ What is the typical age of people attending retreats at Synthesis?
You are over the age of 18 You take a mature approach to your work and relationships You are looking for an experience designed to catalyze deeper self-understanding and personal growth You have a developing interest in the safe and responsible use of psychedelics. See more: 'Is Synthesis right for me?
+ Will my personal information be confidential?
We keep all personal information confidential, none of it will be shared with third parties.
+ Do you offer 1-to-1 guided sessions if I prefer to do this in private?
Yes, we do! Please see our private retreat offer for more details. We also offer 1-to-1 preparation and integration coaching as an option during our group retreats, for an additional fee.
+ Can I do more than one retreat?
Yes, you can. A second retreat can be a quite different experience, certainly not just a repetition. In case it‘s your second overall psychedelic experience, many people tend to be even better prepared and relaxed as there is a familiarity that allows them to let go or direct their experience even more. For experienced psychonauts on the other hand, each experience can have its own focus or topic, exploring different aspects.